WebThe family of diamidophospholipids is discussed in detail from monolayer characterization to the formation of faceted vesicles, culminating in the template-free self-assembly of phospholipid cubes and the possible applications of vesicle origami in modern personalized medicine. Cited By This article is cited by 1 publications.
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WebJul 1, 2024 · The active tuning of the membrane thickness therefore opens new possibilities in the study and manipulation of membrane proteins. Here, we introduce the concept of … WebBilayer Properties of 1,3-Diamidophospholipids Andreas Weinberger,† Radu Tanasescu,† Cristina Stefaniu,§ lllya A. Fedotenko,∥ France Favarger,∥ Takashi Ishikawa,⊥ Gerald Brezesinski,*,§ Carlos M. Marques,*,# and Andreas Zumbuehl*,†,‡ † Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland …
WebArtificial diamidophospholipids are known to form faceted liposomes with interdigitated membrane structure. Here we report a formation and characterization of planar lipid bilayers from an artificial C16-1,3-diamidophospholipid utilizing aparallel lipid bilayer platform based on a microelectrode cavity array (MECA) chip. WebA small library of 1,3-diamidophospholipids containing various acyl chain lengths. We finally identified phosphorodichloridate 3 as a versatile Amide bond formation with long chain acyl chlorides led to the platform for our …
WebA straightforward synthesis of a small library of 1,3-diamidophospholipids is presented using readily available, cheap reagents and introducing a simple phosphoramidate protecting group strategy. Keywords : Nonnatural phospholipids — Phospholipid synthesis — Phosphatidyl ethanolamine — Amine-bearing phospholipids — Phospholipid … WebAmerican Chemical Society; American Chemical Society (ACS) (ISSN 0743-7463), Langmuir, #30, 29, pages 9428-9435, 2013 jul 17
WebOct 13, 2010 · A straightforward synthesis of a small library of 1,3-diamidophospholipids is presented using readily available, cheap reagents and introducing a simple …
WebOct 12, 2010 · The synthesis of 1,3-diamidophospholipids (2010) Illya Fedotenko 29 Citations. A straightforward synthesis of a small library of 1,3-diamidophospholipids is … filthy frank it\u0027s aWebJan 19, 2015 · Bilayer Properties of 1,3-Diamidophospholipids Langmuir A series of 1,3-diamido phosphocholines was synthesized, and their potential to form stable bilayers was investigated. Large and giant unilamellar vesicles produced from these new lipids form a wide variety of faceted liposomes. filthy frank it\u0027s time to stopWebJul 1, 2024 · Here, we introduce the concept of stapling phospholipids to different degrees of interdigitation depth by mixing 1,3-diamidophospholipids with single-chain bolalipids. grp roof finishWebApr 17, 2024 · Diamidophospholipids with C16 tails proved to be an effective building block for mechanoresponsive vesicles, but their low main phase transition temperature prevents an effective application in humans. As the main phase transition temperature of a membrane depends on the fatty acyl chain length, we grp roofing supplies corkWebDihydrolipoamide. Dihydrolipoamide, which in plants is a cofactor associated with the mitochondrial and plastid pyruvate dehydrogenase complexes (mtPDC, ptPDC), … filthyfrank laptopWebMar 3, 2024 · As the main phase transition temperature of a membrane depends on the fatty acyl chain length, we synthesized a C17 homologue of a 1,3-diamidophospholipid: Rad-PC-Rad. The elevated main phase transition temperature of Rad-PC-Rad allows mechanoresponsive drug delivery at body temperature. filthy frank know your placeWebJan 16, 2015 · A series of long-tail alkyl ethanolamine analogs containing amide-, urea-, and thiourea moieties was synthesized and the behavior of the corresponding monolayers was assessed on the Langmuir-Pockels trough combined with grazing incidence X-ray diffraction experiments and complemented by computer simulations. grp roof for bay window